Hepburn masterminded her own comeback, buying out her contract with RKO Radio Pictures and acquiring the film rights to The Philadelphia Story, which she sold on the condition that she be the star.
With her unconventional lifestyle and the independent characters she brought to the screen, Hepburn epitomized the "modern woman" in the 20th-century United States and is remembered as an important cultural figure.
The screen-partnership spanned 25 years and produced nine movies.
Hepburn challenged herself in the latter half of her life, as she regularly appeared in Shakespearean stage productions and tackled a range of literary roles.
After a period of inactivity and ill health, Hepburn died in 2003 at the age of 96.
Hepburn famously shunned the Hollywood publicity machine and refused to conform to society's expectations of women.After four years in the theatre, favorable reviews of her work on Broadway brought her to the attention of Hollywood.